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CD3 抗体

This anti-CD3 antibody is a 小鼠 单克隆 antibody detecting CD3 in FACS, IP, IHC (fro) 和 Func. Suitable for Pig.
产品编号 ABIN371285
发货至: 中国

Quick Overview for CD3 抗体 (ABIN371285)

抗原

See all CD3 抗体
CD3

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

PPT3
  • 特异性

    This antibody recognizes Porcine CD3e (Mr. 20 kDa). The Monoclonal antibody PPT3 is Mitogenic when presented to peripheral blood mononuclear cells in immobilized form. (Ref.1)

    产品特性

    Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). Immunoprecipitation In vitro activation of T cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD3

    别名

    CD3

    背景

    CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains (designated as gamma, delta, epsilon, zeta and eta) ranging in size from 16-28 kDa. CD3 epsilon is closely associated with the T cell antigen receptor (TCR), and is present on thymocytes, CD8+ and CD4+ positive cells. The CD3 epsilon complex mediates signal transduction. It plays a major role in signaling during antigen recognition, leading to T cell activation. The TCR/CD3E complex of T lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3 epsilon is expressed on all T cells of all mouse strains.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

    基因ID

    397455

    UniProt

    Q7YRN2

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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